BioAnalyzer Microarray

Available Versions:

 

• Micro Titer Plate Imaging
• UV Excitation
• High Resolution Imaging

 

All versions utilize LaVision BioTec‘s innovative white light excitation concept in combination with up to date CCD technology. Both provide unmatched flexibility. Just the change of standard filters adapts the instrument on almost any dye.

Dark Field Fluorescence illumination

This technique delivers high signal to noise ratio and provides a sensitivity that is better than 0,06 fluorophores per µm2 – but the technique is limited to flat substrates.

EPI Fluorescence illumination

EPI fluorescence is not limited to flat substrates as it excites and detects fluorescence by common objective lens from the top. Thus it is the perfect choice for microtiterplate imaging.

BioAnalyzer 4 EPI

 

Optics of the BioAnalyzer EPI have been completely redesigned to allow efficient illumination and imaging inside well structures like micro titer plates.

The EPI-fluorescence system has been developed to combine optical resolution of 5µm per pixel with high numerical aperture and therefore brilliant sensitivity over spectral range from 395-750nm.

Fast motorized sample positioning allows overviews with full resolution up to 180x200mm2 within one image. FIPS software allows fully automated plate movement and reading of (e.g.) 96 wells within 30 seconds. Additionally, sub-grids and sub-areas can be user defined and evaluated automatically.

Optics of the BioAnalyzer have been redesigned to increase the optical resolution. High aperture and long a distance objective lens have been introduced into the optical setup. Mechanical stability of the assembly has been improved to suppress smearing effects of the image. With standard CCD one image covers an area of 5.0x3.8mm2. Fast motorized sample positioning allows overviews with full resolution up to 40x50mm2 within one image. Dark field illumination of the sample gives brilliant images and excellent contrast.

The BioAnalyzer 4F can be equipped with an optional UV Kit that contains:

• Quartz Lenses in Excitation Light Path
• UV transmitting light guide
• Special Filters

 

The UV Kit option allows the user to excite native Fluorescence and UV dyes.