Benefits


  •  One scan head – two stands
  •  Cost-effective choice for multi-user labs
  •  Flexible and modular system
  •  Fast intravital imaging with Cloud scanner and resonant scanner
  •  Photo-treatment and Optogenetic Modulation
  •  Integrated FLIM imaging

For each stand the user can choose the best detection components: up to 6 NDD detectors (GaAsP, GaAs, hybrid, or standard), up to 2 NDD GaAsP detectors for resonant scanning, and FLIM detectors for both stands. Additional, a transmission port with up to 2 NDD detectors can be integrated into the upright stand.

Specifications


Combinable with all of LaVision BioTec’s TriM Scope extensions:

  •  Cloud Scanner
  •  4X Cloud Scanner
  •  Dual Scanner
  •  Resonant scanner
  •  FLIM x16 TCSPC detector
  •  FLIM x1 TCSPC detector
  •  Adaptive Optics

Doubleheader

Combined inverted and upright 2-P microscopes sharing one scan head

The Doubleheader system combines a single scan head with both upright and inverted stands which can be used alternately. It is the perfect, cost-effective choice if the 2-photon microscope is required for diverse applications such as in a multi-user environment.

To move from one stand to the other, the user pushes one slider and makes just one click in the software – it’s that easy – without further alignments! These are not necessary because the laser beam first goes through the scanner (galvo and resonant scanner) and is then deflected to the chosen stand. This means that both stands also share the same excitation lasers, and if integrated into the system, the same 4X Cloud Scanner, Cloud Scanner, and Adaptive Optics Module.

Applications with an inverted stand


Brain slice imaging, cell culture imaging, fixed tissue imaging, organ ex vivo imaging, liver in vivo imaging, kidney in vivo imaging, intestine in vivo imaging.

Applications with an upright stand


Brain imaging in vivo, bone marrow in vivo imaging, lymph node in vivo imaging, calcium imaging, and combinations with electro-physiological applications.

Hosts up to


  •  2 OPOs
  •  2 Ti:Sapphire lasers (may be integrated with Spectra Physics InSight®1 Dual)
  •  5 visible laser lines
  •  6 NDD detectors (e.g. GaAsP, GaAs, Hybrid or Standard)
  •  2 NDD GaAsP detectors for resonant scanning

Z-stack of a bone marrow chimera animal that highlights the lymphatics and vasculature within a lymph node. By courtesy of Ann Haberman and David Gonzalez, School of Medicine, Yale University, USA